A recent study suggests that individuals who stop using new slimming jabs like semaglutide or tirzepatide may regain reduced body mass far faster than those who end traditional diet and exercise regimens.
Findings released in a leading health publication demonstrates that while obese individuals often shed substantial amounts of their total mass while undergoing treatment, the weight is regained at an average rate of 0.8 kg per month after stopping.
"People purchasing these drugs must be informed of the risk of quick weight regain when the therapy is stopped," cautioned expert Dr. Susan Jebb.
Such speed of regain implies a reversion to original weight within about a year and a half.
Weighing Treatments
The analysis, which examined dozens of studies involving over 9,000 of participants, compared the effects of the injectable medications with other pills.
Researchers emphasize that people who shed pounds through dieting usually see a slower creep back—around 0.1 kg a month—post-intervention.
Understanding the Quick Rebound
Nutrition scientists believe the mechanism of the jabs accounts for the amplified weight return.
These medications mimic a natural hormone called glucagon-like peptide-1, which helps regulate appetite.
"Long-term administration of the hormone levels several times higher than normal may cause the body to produce less of its own natural hormone, and could diminish responsiveness to its actions," explained Dr. Adam Collins, a dietetics expert.
"Stopping of this medication results in hunger is unsuppressed, making overeating a significant risk."
An Ongoing Condition?
Health authorities recommend the jabs for individuals with obesity-related health risks, accompanied by prescribed diet and exercise modifications.
Professionals contend that, due to the likelihood of relapse, the therapy is often long-term.
This opinion is echoed by drug manufacturers, who state that the findings "underscore the long-term nature of excess weight," akin to managing conditions like high blood pressure.
Patient Experiences
People who have stopped the medication describe a sudden return of appetite.
"It felt as if something flipping and I was suddenly starving," recalled an individual.
This difficulty is compounded if patients have not adopted lasting dietary or behavioural modifications during therapy.
Significant Use
Recent estimates show that millions of people in the UK have used these injections in the past year, with demand continuing to grow.
- Use is greater among females than men.
- The middle-aged demographic shows the greatest usage rates.
- Many obtain the medications through private healthcare rather than public health services.
Finally, clinicians caution that while the jabs are powerful agents for weight loss, they are not a permanent cure and long-term success relies on ongoing lifestyle management.
